- Unsatisfactory Specimens: Interpretations, Studies and Current Trends Recording and Presentation
- Influence of Hematocrit and Total-Spot Volume on Performance Characteristics of Dried Blood Spots for Newborn Screening
- Newborn screening blood spot analysis in the UK: influence of spot size, punch location and haematocrit
Assuring Laboratory Quality
Maintaining trust in newborn screening results is essential to the success of programs across the country. We help assure the proficiency and quality of newborn screening test results through emergency coordination, policy guidance and improvements to information exchange processes.
Contact the Newborn Screening and Genetics team: [email protected]
CDC Newborn Screening Quality Assurance Program
APHL partners with the US Centers for Disease Control and Prevention (CDC) to ensure the quality and accuracy of newborn screening test results at public health laboratories through emergency coordination, policy guidance and improved data exchange. The CDC’s Newborn Screening Quality Assurance Program (NSQAP), operated by the Newborn Screening Molecular Biology Branch, is a voluntary, non-regulatory initiative serving over 670 laboratories worldwide. NSQAP provides dried blood spot reference materials, distributes coded specimens to assess lab proficiency, and works with labs to correct errors and improve practices. Quarterly reports help laboratories benchmark their performance against peers.
Quality Assurance Resources
General Resources
- Newborn Screening Analyte Interference List webpage
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Cutoff Determinations and Risk Assessment Methods
This report provides a general overview of the variety of approaches utilized by newborn screening laboratories and program staff to determine if a newborn is at risk for a screened disorder.